Our Publications & Abstracts

Iron-Sulfur Clusters and Iron Responsive Element Binding Proteins Mediate Iron Accumulation in Corneal Endothelial Cells in Fuchs Dystrophy - PubMed

Hartness EM, Shevalye H, Skeie JM, Eggleston T, Field MG, Schmidt GA, Phruttiwanichakun P, Salem AK, Greiner MA. Iron-Sulfur Clusters and Iron Responsive Element Binding Proteins Mediate Iron Accumulation in Corneal Endothelial Cells in Fuchs Dystrophy. Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):23. doi: 10.1167/iovs.66.4.23. PMID: 40202733; PMCID: PMC11993131

Corneal transplantation wound dehiscence after penetrating keratoplasty and deep anterior lamellar keratoplasty - PubMed

Sarin SR, Greiner MA, Schmidt GA, Matharu KS, Goins KM, Kitzmann AS, Ling J, Wagoner MD, Sales CS, Silverman JIM. Corneal transplantation wound dehiscence after penetrating keratoplasty and deep anterior lamellar keratoplasty. Int Ophthalmol. 2025 Sep 5;45(1):373. doi: 10.1007/s10792-025-03708-x. PMID: 40911254

TCF4 trinucleotide repeat expansions and UV irradiation are associated with ferroptosis susceptibility in Fuchs endothelial corneal dystrophy | bioRxiv

Saha S, Skeie JM, Schmidt GA, Eggleston T, Shevalye H, Sales CS, Phruttiwanichakun P, Dusane A, Field MG, Rinkoski TA, Fautsch MP, Baratz KH, Roy M, Jun AS, Pendleton C, Salem AK, Greiner MA. TCF4 trinucleotide repeat expansions and UV irradiation increase susceptibility to ferroptosis in Fuchs endothelial corneal dystrophy. Redox Biol 2024;77:103348

Rat Model of Type 2 Diabetes Mellitus Recapitulates Human Disease in the Anterior Segment of the Eye - PubMed

Wang CL, Skeie JM, Allamargot C, Goldstein AS, Nishimura DY, Huffman JM, Aldrich BT, Schmidt GA, Teixeira LBC, Kuehn MH, Yorek M, Greiner MA. Rat Model of Type 2 Diabetes Mellitus Recapitulates Human Disease in the Anterior Segment of the Eye. Am J Pathol 2024;194:1090-1105

Type II Diabetes Mellitus Causes Extracellular Matrix Alterations in the Posterior Cornea That Increase Graft Thickness and Rigidity

Kingsbury KD, Skeie JM, Cosert K, Schmidt GA, Aldrich BT, Sales CS, Weller J, Kruse, F, Thomasy, SM, Schlötzer-Schrehardt U, Greiner MA. Type II Diabetes Mellitus Causes Extracellular Matrix Alterations in the Posterior Cornea That Increase Graft Thickness and Rigidity. Invest. Ophthalmol. Vis. Sci. June 2023; 64(7):26. PMID: 37326594

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy | IOVS | ARVO Journals

Leonard BC, Park S, Kim S, Young LJ, Jalilian I, Cosert K, Zhang X, Skeie JM, Shevalye H, Echeverria N, Rozo V, Gong X, Xing C, Murphy CJ, Greiner MA, Mootha VV, Raghunathan VK, Thomasy SM. Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci 2023;64(4):22

Metabolic indications of diabetes progression in human aqueous humor | IOVS | ARVO Journals

Fortenbach CR, Skeie JM, Sevcik KM, Johnson AT, Oetting TA, Haugsdal JM, Sales CS, Nishimura DY, Taylor EB, Schmidt GA, Greiner MA. Metabolic and proteomic indications of diabetes progression in human aqueous humor. PLoS One 2023;18(1):e0280491

Mitophagy: An Emerging Target in Ocular Pathology

Skeie JM, Nishimura DY, Wang CL, Schmidt GA, Aldrich BT, Greiner MA. Mitophagy: An Emerging Target in Ocular Pathology. Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):22. PMID: 33724294

Solubilized ubiquinol for preserving corneal function

Naguib YW, S Sanjib, Skeie JM, Acri T, Ebeid K, Abdel-Rahman S, Kesh S, Schmidt GA, Nishimura DY, Banas JA, Zhu M, Greiner MA, Salem AK. Solubilized Ubiquinol for Preserving Corneal Function. Biomaterials 2021. Aug;275:120842. PMID: 34087583

Optimizing Visualization of Descemet Membrane Endothelial Keratoplasty Tissue: Assessing the Impact of Trypan Blue Exposure on Stain Duration and Corneal Endothelial Cell Function

Ling JJ, Kyrillos R, Burckart KA, Aldrich BT, Skeie JM, Schmidt GA, Conwell C, Ramirez T, Reed CR, Zimmerman MB, Greiner MA, Li JY. Optimizing Visualization of Descemet Membrane Endothelial Keratoplasty Tissue: Assessing the Impact of Trypan Blue Exposure on Stain Duration and Corneal Endothelial Cell Function. Cornea. 2021 Mar 1;40(3):292-298. PMID: 32732698.

Review: Optimizing DMEK Technique, 2018-2020

Ramirez DA, Schmidt GA, Worthington KS, Sales CS. Review: Optimizing DMEK Technique, 2018-2020. Int Ophthalmol Clin. 2021 Jan 1;61(1):45-55. PMID: 33337793.

Potential Functional Restoration of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy by ROCK Inhibitor (Ripasudil)

Schlötzer-Schrehardt U, Zenkel M, Strunz M, Gießl A, Schondorf H, da Silva H, Schmidt GA, Greiner MA, Okumura N, Koizumi N, Kinoshita S, Tourtas T, Kruse FE. Potential functional restoration of corneal endothelial cells in Fuchs endothelial corneal dystrophy by ROCK inhibitor (ripasudil). Am J Ophthalmol. 2021 Apr;224:185-199. PMID: 33316261.

Efficacy and Safety of Various Amphotericin B Concentrations on Candida albicans in Cold Storage Conditions.

Tran KD, Aldrich BT, DʼAmato Tóthová J, Skeie JM, Kondratick CM, Giurgola L, Gatto C, Reed CR, Schmidt GA, Terry MA, Greiner MA. Efficacy and Safety of Various Amphotericin B Concentrations on Candida albicans in Cold Storage Conditions. Cornea. 2020 Jan;39(1):110-117. doi: 10.1097/ICO.0000000000002019. PMID: 31206398

Ubiquinol Supplementation of Donor Tissue Enhances Corneal Endothelial Cell Mitochondrial Respiration

Skeie JM, Aldrich BT, Nishimura DY, Schmidt GA, Zimmerman MB, Ling JJ, Naguib YW, Salem AK, Greiner MA. Ubiquinol Supplementation of Donor Tissue Enhances Corneal Endothelial Cell Mitochondrial Respiration. Cornea. 2020 Oct;39(10):1285-1290. PMID: 32558735.

DMEK Outcomes Using Nondiabetic Grafts for Recipients with Diabetes Mellitus

Janson BJ, Terveen DC, Benage MJ, Zimmerman MB, Mixon DC, Aldrich BT, Skeie JM, Schmidt GA, Reed CR, Goins KM, Greiner MA.  DMEK Outcomes using Nondiabetic Grafts for Recipients with Diabetes Mellitus. Am J Ophthalmol Case Rep. 2019 Jul 9;15:100512. doi: 10.1016/j.ajoc.2019.100512. eCollection 2019 Sep. PMID: 31341996

Donor, Recipient, and Operative Factors Associated With Increased Endothelial Cell Loss in the Cornea Preservation Time Study.

Lass, JH, Benetz, BA, Patel, SV, Szczotka-Flynn LB, O’Brien R, Ayala, AR, Maquire, MG, Daoud, YJ, Greiner, MA, Hannush, SB, Lee, B, Mauger, TF, Menegay, HJ, Mifflin, MD, Raizman, MB, Rose-Nussbaumer, J, Schultze, RL, Schmidt, GA, Sugar, A, Terry, MA, Verdier, DD. Donor, Recipient, and Operative Factors Associated With Increased Endothelial Cell Loss in the Cornea Preservation Time Study. JAMA Ophthalmol.  2019;137(2):185-193